Who IV Ketamine Therapy & Spravato® Can Help

Why We Specialize in Ketamine Therapy for Depression

The majority of research on ketamine in mental health has centered on depression, making it the most extensively studied condition for this treatment. Decades of data highlight both IV ketamine and Spravato® (esketamine) as leading options for individuals struggling with depressive symptoms — with IV ketamine representing the most validated method of administration and Spravato® offering an FDA-approved, insurance-covered alternative.

Both IV ketamine therapy and Spravato® have consistently demonstrated the ability to ease depression more effectively and more rapidly than many traditional antidepressants. While conventional medications often take weeks to show benefit and can bring unwanted side effects, ketamine offers a faster, more targeted path to relief — with some patients noticing meaningful changes within hours to days of their first session.

Our commitment is clear: to deliver the highest standard of IV ketamine therapy and Spravato® treatment for those seeking relief from depression, PTSD, trauma, and anxiety. We focus on safety, individualized care, and clinical excellence on being the best possible choice for the patients we serve across Philadelphia, Rittenhouse Square, the Main Line, Bucks County, and surrounding communities.

Mental health is complex, and depression rarely exists in isolation. At Better Health, we recognize that many patients face overlapping challenges, and we tailor care to meet those realities. Alongside depression, we often support individuals who are also:

With the right clinical and personal support systems in place, both IV ketamine and Spravato® can help reduce intrusive thought patterns and provide meaningful relief. Spravato® is specifically FDA-approved for adults with major depressive disorder experiencing suicidal ideation, making it an important option for patients needing more immediate support.

We collaborate with therapists to ensure trauma survivors can process difficult memories in a safe, supportive environment.

Some patients experience depression alongside substance use or during recovery. We provide care that respects both journeys.

We offer evidence‑based treatment options for new mothers seeking relief from depression after pregnancy.

We’ve safely treated patients 65 and older, helping improve quality of life and restore hope.

Depression and anxiety often occur together. By treating depression with ketamine therapy, patients are better able to manage their anxiety symptoms.

We provide care for individuals experiencing the depressive phases of Bipolar I and Bipolar II.